Prof Marija Krstic-Demonacos

School of Science, Engineering & Environment

Photo of Prof Marija Krstic-Demonacos

Current positions

Professor

Biography

I took up my Chair in Molecular Medicine in the School of Environment and Life Sciences in April 2013 where I was director of Biomedical Research Centre from 2014-2022. Prior to this I was a Welcome Trust Fellow and Lecturer in the University of Manchester from 2003. I completed my PhD in molecular endocrinology in the University of California San Francisco and postdoctoral studies in cancer biology in Glasgow University. I have published in reputed journals and have been serving as an editorial board member of several international journals. In addition, commercialization potential of my research is evidenced by the three patents I own. I have presented at numerous conferences and served as reviewer for many international funding bodies and journals.

Areas of Research

Cellular response to stress and hormonal signals

My main research interests focus is on the investigation of the molecular mechanisms governing the regulation of gene expression in normal and cancer cells and in particular the (A) analysis of the function of steroid receptors, (B) the role of tumor suppressor p53. We study leukemia, lung, breast and other types of cancer as well as inflammatory processes, using molecular biology, biochemistry, cell biology, translational medicine and bioinformatics-based methods. Overall, I concentrate my research efforts on addressing important questions towards characterising the mechanisms of gene expression and signaling pathways in pathological conditions towards improving clinical practice. I pursue scientific excellence using diverse funding sources and forming strong networks of highly productive local, national and international collaborations. I serve as editor and reviewer of numerous biomedical journals and funding bodies and have been a member of several scientific societies.

Teaching

Module leader for Pathologies of Human disease
Module leader for Novel Therapeutics
Past module leader for Medical Biotechnology
Development of MSc Biomedical Science taught course with five 30 credit modules.
Delivery of lectures, tutorials and supervision of undergraduate/MSc projects as well as all types of assessment procedures across different degrees

Qualifications and Recognitions

Qualifications
  • PhD in Endocrinology

    1995