Dr Allen is a cell pathologist with a research interest in host-pathogen interactions, inflammation and fibrosis. His work has explored the use of antibody therapies, ‘nutriceutical’ anti-inflammatory and anti-fibrotic therapeutics using in vitro models of skeletal muscle and lung fibrosis.
Dr Aziz is an immunologist interested in understanding the basic biological mechanism of gene transcription, cellular aging and how this relates to cancers, including Acute Myeloid Leukemia (AML).
Dr Brookes is a molecular parasitologist with expertise in parasite/nematode proteases. He also has a research interest in the parasitic infections of threatened species of wildlife, including pipistrelle bats and the European eel.
Dr Elder has many years’ experience in the field of DNA damage and repair, particularly in the area of base excision repair (BER). DNA glycosylases are enzymes that ‘search and remove’ chemically altered bases from the DNA molecule in the first step of BER. Current research is focussed on a DNA glycosylase called NEIL3. This protein has a unique structure, is highly expressed in many cancer cells and has been shown to be essential for HIV replication.
Professor Howard Foster is a microbiologist with interests in bacterial pathogenicity especially Staphylococcus aureus, antimicrobial coatings for surfaces and novel antimicrobial agents.
Dr David Greensmith is a cardiac cellular electrophysiologist. Using patch-clamping and real-time fluorescent imaging, he investigates how cytokines and oxidative stress affect calcium handling in single heart cells. This is to provide a cellular basis for cardiac dysfunction in diseases such as sepsis.
Dr John Hadfield is a medicinal chemist with a specific interest in the design and development of anticancer drugs. The research is focussed on antivascular agents as well as on the development of methods for the multiphoton isomerisation of stilbenes to transform inactive, non-toxic agents into useful therapeutics.
Dr Chloe James is a microbiologist with chief interests in bacterial pathogenicity, communication within polymicrobial communities; development and spread of antibiotic resistance and bacteriophages.
Professor Marija Krstic-Demonacos is molecular biologist with research interests in cancer and inflammation. Specific areas include childhood and environmentally-induced cancer, endocrinology, bioinformatics, stem cells and translational biomedical research.
Dr Gemma Lace-Costigan is a neurobiologist with a specific interest in neurodegenerative disease’s such as Alzheimer’s Disease, Parkinson’s Disease and Frontotemporal Lobar Degeneration. Her research projects focus on the investigation of disrupted protein degradation pathways, the inhibition of neuron to neuron spread of disease pathogenesis, the role of glial cells and the contribution of inflammation to neurodegeneration
Prof Andy Miah is an English bioethicist, academic and journalist. His research discusses ethical and cultural issues arising from new technologies and is informed by an interest in applied philosophy, technology, and culture.
Prof Luciano Mutti is a MD whose activity lays within trnslational cancer research with particular interest in thoracic malignancies.
Dr Nirmalan is a molecular parasitologist whose research focuses on anti-malarial drug discovery. Other intrests include the development of proteomic/mass spectrometric methods to define mechanisms of antimalarial drug action.
Dr Ian Podmore is a bio-analytical chemist who has an interest in the development of assays to measure biomarkers of disease, particularly those involving free radicals. He specializes in the use of chromatography and mass spectrometry techniques for the separation and detection of markers of free radical induced cellular damage.
Dr Pye is a biochemist who leads research projects in the field of cancer therapeutics, antimicrobial drug discovery, applications of glycomics in medical diagnosis and molecular drug design.
Dr Patricia Ragazzon is a chemist with interests in different areas of chemistry and biology. Currently, her research projects focus in the development on small molecules as anticancer and antimicrobials agents, toxicological studies in vitro, aptamer development and natural products.
Dr Rossington is a chemist whose research focuses on the development of methodology involving chiral lithium amide bases, antibacterial agent development and glycoaminoglycan isolation.
Dr Lucy Smyth is a Lung and inflammation immunologist. Key areas of research include Chronic Obstructive Pulmonary Disease (COPD) and asthma with ongoing clinical studies investigating immune and fibrotic processes in lung disease. Collaborative research interests also extend into neurodegenerative diseases, trauma injury and cancer immunology.
Dr Jim Wilkinson is an organic chemist with research interests in synthetic methodology and medicinal chemistry. Specific areas include organolithium chemistry in synthesis and the design and development of anticancer and antimalarial drugs.