Steven Rossington

Dr Steven Rossington

Lecturer in organic chemistry

Office Times

Tuesday 9:00am -10:00am, Friday 9:00am -10:00am

Biography

I am currently a lecturer in physical-organic chemistry at the university and the Admission Tutor for the chemistry programme area. I joined the University of Salford in 2008 after Postdoctoral periods at the Manchester Interdisciplinary Biocentre, Manchester University, Liverpool University and a Research Assistance role at Salford University.

My research is mainly on the development of methodology involving chiral lithium amide bases, antibacterial agent development and glycoaminoglycan isolation

Teaching

L3 Chemical Principles (Module Lead), L3 Scientific Methods (Module Lead), L4 Organic Chemistry

Research Interests

Organic chemistry – synthesis of small biological molecules and methodology. Chemistry pedagogy – evaluation of chemistry university teaching practices on L3 students. 

Qualifications and Memberships

BSc(Hons) Chemistry – University of Salford

PhD in Organic Chemistry – University of Salford

Publications

S.B.Rossington, J.A. Hadfield, S.D. Shnyder, T.W. Wallace, Tubulin-binding dibenz[c,e]oxepines: Part 2. 1 Structural variation and biological evaluation as tumour vasculature disrupting agents, Bioorganic and Medicinal Chemistry, 2017, 25, 1630-1642.

S.B. Rossington, Building BORIS - an outreach project on drug design and molcular modelling, The Biochemist, 2017, 38, 6-7.

P.M. Killoran, J.A. Wilkinson, J.A. Hadfield, S.B. Rossington, Expanding the scope of the Babler-Daubin oxidation: 1-3 oxidative transportation of 2o allylic alcohols, Tetrahedron Letters, 2016, 57, 3954-3957.

L.M. Gooch, S.B. Rossington, J.A. Wilkinson, Asymmetric synthesis of diarylmethane derivatives by dynamic kinetic resolution, Tetrahedron Letters, 2015, 56, 4025-4027

I. Slabu, S.B. Rossington, P.M. Killoran, N. Hirst, J.A.Wilkinson, Total synthesis of (+)-mimosifoliol by lateral lithiation, Tetrahedron Letters, 2013, 54, 1498-1490

P.H. Jalily, J.A. Hadfield, N. Hirst, S.B.Rossington, Novel cyanocombretastatins as potent tubulin polymerization inhibitors, Bioorganic and Medicinal Chemistry Letters, 2012, 22, 6731-6734.

D.J. Heyes, C. Levey, P. Lafite, I.S. Roberts, M. Goldrick, A.V. Stachulski, S.B. Rossington, D. Stanford, S.E.J. Rigby, N.S. Scrutton, D. Leys, Structure based mechanism of CMP-KDO Synthase: Convergent evolution of a sugar activating enzyme with DNA-RNA polymerasesJournal of Biological Chemistry, 2009, 284, 35514-35523.

S.B. Rossington, Illustrating drug design using molecular modelling, The Biochemist, 2009, 31, 26-27.

J.A. Wilkinson, S.B. Rossingon, N.A. Coe, N. Hirst, A. McGown, J. Leonard, N. Hussain, Synthesis and evaluation of 2'-substituted fendiline analogues as antileukemics, Letters in Drug Design and Development, 2007, 4, 246-248.

J.A. Wilkinson,  D. Foretia, S.B.Rossington, C. Austin, A.T. Hegarty, J.Leonard, N. Hussain, 2’-Hydroxy-fendiline analogues as potent relaxers of isolated arteries, European Journal of Pharmacology, 2007, 561, 160-163.

J.A.Wilkinson, S.B.Rossington, S.Ducki, J.Leonard, N.Hussain, Asymmetric alkylation of diarylmethane derivatives, Tetrahedron, 2006, 62, 1833-1844.

J.A.Wilkinson, S.B.Rossington, S.Ducki, J.Leonard, N.Hussain, Asymmetric alkylation of N-pivaloyl-o-benzylaniline, Tetrahedron: Asymmetry, 2004, 15, 3011-3013.

J.A.Wilkinson, S.B.Rossington, J.Leonard, N.Hussain, Asymmetric alkylation of diarylmethane derivatives. Improved results using methoxyethoxy substituent, Tetrahedron Letters, 2004, 45, 5481-5483.

J.A.Wilkinson, S.B.Rossington, J.Leonard, N.Hussain, Asymmetric alkylation of diphenylmethane derivatives using (−)-sparteine, Tetrahedron Letters, 2004, 45, 1191-1193.