Professor Roger Bisby

Emeritus Professor

  • Peel Building Room G48
  • T: +44 (0)161 295 4912
  • E: r.h.bisby@salford.ac.uk
  • SEEK: Research profile

Biography

BSc (Nottingham), 1st Class Hons 1969

PhD (Nottingham) 1973

Teaching

Level 6 – Biochemistry of Disease

Level 6 – Final Year Projects

Level 5 – Fundamentals of Biochemistry

Research Interests

Time-resolved spectroscopy of biochemical systems involving free radicals and excited states.

Laser photochemistry

Vitamins and antioxidants

Fluorescence lifetime imaging and multiphoton excitation

Light-activation of drugs

Qualifications and Memberships

BSc (Nottingham), 1st Class Hons 1969

PhD (Nottingham) 1973

Member Biochemical Society

Fellow Royal Society of Chemistry

Fellow Higher Education Academy

Publications

R.H.Bisby, S.W.Botchway, G.M.Greetham, J.A.Hadfield, A.T.McGown, A.W.Parker, K.M.Scherer and M.Towrie. (2012) Time-resolved nanosecond fluorescence lifetime imaging and picosecond infrared spectroscopy of combretastatin A-4 in solution and in cellular systems. Measurement Science and Technology, 23,  084001 (10pp). DOI:10.1088/0957-0233/23/8/084001

R.H.Bisby, S.W.Botchway, A.G.Crisostomo, A.W.Parker and K.M.Scherer (2012) Fluorescence lifetime imaging of propranolol uptake in living glial cells. Spectroscopy 27, 533-540. DOI: 10.1155/2012/518353

R.H.Bisby, S.W.Botchway, J.A.Hadfield, A.T.McGown, A.W.Parker and K.M. Scherer (2012) Fluorescence lifetime imaging of E-combretastatin uptake and distribution in live mammalian cells. European Journal of Cancer, 48, 1896-1903; published online DOI: 10.1016/j.ejca.2011.11.025

R.H.Bisby, S.W.Botchway, A.G.Crisostomo, J.Karolin, A.W.Parker  and L.Schröder (2010) Interactions of the beta-blocker drug, propranolol, with detergents,beta-cyclodextrin and living cells studied using fluorescence spectroscopy and imaging. Spectroscopy - Biomedical Applications 24, 137-142.

F.M.D.Ismail, M.G.B.Drew, S.Navaratnam and R.H.Bisby (2009) A pulse radiolysis study of free radicals formed by one electron oxidation of the antimalarial drug pyronaridine. Research on Chemical Intermediates 35, 363-377. DOI: 10.1007/s11164-009-0051-7.

R.H.Bisby, A.G.Crisostomo, S.W.Botchway and A.W.Parker (2009) Nanoscale Hydroxyl Radical Generation from Multiphoton Ionization of Tryptophan. Photochemistry and Photobiology 85, 353-357. DOI: 10.1111/j.1751-1097.2008.00447.x

S.Kristensen, R.Edge, H.H.Tønnesen, R.H.Bisby and S.Navaratnam (2009) Photoreactivity of biologically active compounds. XIX: Formation and reactivity of excited states and free radicals from primaquine. Journal of Photochemistry and Photobiology B: Biology 94, 147-157. doi:10.1016/j.jphotobiol.2008.11.006

R.H.Bisby, R.Brooke and S.Navaratnam (2008) Effect of antioxidant potential in the oxygen radical absorption capacity (ORAC) assay. Food Chemistry 108, 1002-1007.  DOI:-  10.1016/j.foodchem.2007.12.012

S.W.Botchway,  A.W.Parker, R.H.Bisby and A.G.Crisostomo (2008) Real-time cellular uptake of serotonin using fluorescence lifetime imaging with two-photon excitation. Microscopy Research and Technique 71, 267–273. DOI: 10.1002/jemt.20548

S.W.Botchway, A.G.Crisostomo, A.W.Parker and R.H.Bisby (2007) Near Infrared Multiphoton-induced generation and detection of hydroxyl radicals in a biochemical system. Archives of Biochemistry and Biophysics 464, 314-321. doi:10.1016/j.abb.2007.04.026

A.G.Crisostomo, R.B.Moreno, S.Navaratnam, J.A.Wilkinson and R.H.Bisby (2007) Generation of reactive oxygen species from a-tocopherolquinone and analogues. Free Radical Research 41, 730-737. doi:10.1080/10715760701324075