Researcher secures over £14,000 worth of funding to discover why the heart fails in patients with sepsis

Wednesday 22 April 2015
Dr David Greensmith has secured over £14,000 worth of funding to discover why the heart fails in patients with sepsis.
Dr David Greensmith has secured over £14,000 worth of funding to discover why the heart fails in patients with sepsis.

A researcher from the School of Environmental and Life Sciences (ELS), Dr David Greensmith, has secured over £14,000 worth of funding to discover why the heart fails in patients with sepsis.

Dr Greensmith’s research in collaboration with the University of Manchester will enable a cellular investigation discovering why the heart fails in people with sepsis, which affects approximately 30 million people globally with 50% mortality.

Normally, infections are contained in a single part of the body; however, in sepsis infection spreads throughout the body.

The subsequent immune response damages the tissues and organs – such as the heart – leading to severe illness and death.

The objective of the study is to investigate mechanisms of heart failure and, in particular, how signalling molecules cytokines change the way calcium rises and falls in heart cells, and how this results in poor heart cell contraction.

Dr Greensmith received the funding from the Royal Society Early Career Research Grant.